Polymorphism of MTHFR C677T Gene and the Associations with the Severity of Essential Hypertension in Northern Chinese Population

Table 6

Multivariate logistical regression analysis for hypertension classification.

Variables	β	OR (95% CI)	value
Smoking
Yes	0.711	2.04 (1.29–3.22)	0.002^b
No	—	1	—
Family history of hypertension
Yes	0.595	1.81 (1.11–2.97)	0.018^a
No	—	1	—
MTHFR C677T genotype
TT	0.807	2.24 (1.14–4.39)	0.019^a
CT	0.83	2.29 (1.29–4.08)	0.005^b
CC	—	1	—
Homocysteine (μmol/l)	0.035	1.04 (1.01–1.06)	0.003^b
Triglycerides (mmol/l)	0.23	1.26 (1.00–1.58)	0.047^a

^a. ^b. OR: odds ratio; CI: confidence interval; MTHFR: methylenetetrahydrofolate reductase.