Research Article
Polymorphism of MTHFR C677T Gene and the Associations with the Severity of Essential Hypertension in Northern Chinese Population
Table 6
Multivariate logistical regression analysis for hypertension classification.
| Variables | β | OR (95% CI) | value |
| Smoking | | | | Yes | 0.711 | 2.04 (1.29–3.22) | 0.002b | No | — | 1 | — | Family history of hypertension | | | | Yes | 0.595 | 1.81 (1.11–2.97) | 0.018a | No | — | 1 | — | MTHFR C677T genotype | | | | TT | 0.807 | 2.24 (1.14–4.39) | 0.019a | CT | 0.83 | 2.29 (1.29–4.08) | 0.005b | CC | — | 1 | — | Homocysteine (μmol/l) | 0.035 | 1.04 (1.01–1.06) | 0.003b | Triglycerides (mmol/l) | 0.23 | 1.26 (1.00–1.58) | 0.047a |
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a. b. OR: odds ratio; CI: confidence interval; MTHFR: methylenetetrahydrofolate reductase. |