Combination of Exercise Training and SOD Mimetic Tempol Enhances Upregulation of Nitric Oxide Synthase in the Kidney of Spontaneously Hypertensive Rats

Table 1

The SBP and biochemical variables in SHR control and WKY control.

	WKY	SHR
	Control (n = 10)	Control (n = 10)
SBP (mmHg)	153 ± 8	225 ± 6
DBP (mmHg)	105 ± 4	130 ± 5
Body weight (g)	378 ± 16	386 ± 15
Kidney weight/body weight (g/kg)	6.21 ± 0.53	6.48 ± 0.27
Total cholesterol (mg/dl)	69 ± 4.55	64.40 ± 2.08
Triglyceride (mg/dl)	32.17 ± 3.27	53.00 ± 4.39
Free fatty acid (mEq/l)	0.24 ± 0.02	0.21 ± 0.01
Glucose (mg/dl)	177.17 ± 5.36	199.80 ± 5.62
Plasma H2O2 (umol/L)	1.71 ± 0.22	3.51 ± 0.18
Urine H2O2 (nmol/day)	19.73 ± 1.46	26.45 ± 1.24
Plasma NOx (umol/L)	9.78 ± 0.39	16.55 ± 0.39
Urine NOx (umol/day)	0.30 ± 0.03	0.53 ± 0.03
Renal cotex NADPH oxidase activity (counts/min/mg)	6624 ± 388	27743 ± 687
Renal outer medulla NADPH oxidase activity (counts/min/mg)	6362 ± 368	21038 ± 625
Aorta NADPH oxidase activity (counts/min/mg)	13352 ± 487	43644 ± 866
Plasma creatinine (mg/dl)	0.19 ± 0.01	0.17 ± 0.01
Creatinine clearance (ml/min)	2.15 ± 0.31	2.50 ± 0.51
Plasma urea nitrogen (mg/dl)	18.88 ± 0.63	17.86 ± 0.60

Values are means ± SEM. vs. the WKY control group. vs. the WKY control group.