Combination of Exercise Training and SOD Mimetic Tempol Enhances Upregulation of Nitric Oxide Synthase in the Kidney of Spontaneously Hypertensive Rats
Table 2
Effects of Ex and tempol on the SBP and biochemical variables in SHR.
Control (n = 10)
Ex (n = 10)
Tmp (n = 10)
Ex + Tmp (n = 10)
SBP (mmHg)
225 ± 6
211 ± 4
212 ± 6
202 ± 4
DBP (mmHg)
130 ± 5
122 ± 5
125 ± 3
123 ± 3
Body weight (g)
386 ± 15
350 ± 23
366 ± 13
358 ± 19
Kidney weight/body weight (g/kg)
6.48 ± 0.27
5.93 ± 0.19
6.04 ± 0.29
6.12 ± 0.11
Total cholesterol (mg/dl)
64.40 ± 2.08
61.80 ± 2.35
59.20 ± 2.11
59.00 ± 2.25
Triglyceride (mg/dl)
53.00 ± 4.39
61.40 ± 4.66
51.80 ± 5.75
61.20 ± 5.04
Free fatty acid (mEq/l)
0.21 ± 0.01
0.20 ± 0.02
0.20 ± 0.02
0.18 ± 0.02
Glucose (mg/dl)
199.80 ± 5.62
187.80 ± 5.85
187.00 ± 7.50
193.40 ± 4.12
Plasma creatinine (mg/dl)
0.17 ± 0.01
0.11 ± 0.02
0.14 ± 0.02
0.08 ± 0.01
Creatinine clearance (ml/min)
2.50 ± 0.51
4.57 ± 0.67
3.28 ± 0.46
5.82 ± 0.75
Plasma urea nitrogen (mg/dl)
17.86 ± 0.60
17.34 ± 0.75
17.28 ± 0.73
16.78 ± 0.79
Values are means ± SEM. vs. the control group. vs. the control group. vs. the Ex group. vs. the Tmp group.
