Research Article

Combination of Exercise Training and SOD Mimetic Tempol Enhances Upregulation of Nitric Oxide Synthase in the Kidney of Spontaneously Hypertensive Rats

Table 3

Effects of Ex and tempol on the SBP and biochemical variables in WKY.

Control (n = 10)Ex (n = 10)Tmp (n = 10)Ex + Tmp (n = 10)

SBP (mmHg)153 ± 8155 ± 5153 ± 6154 ± 6
DBP (mmHg)105 ± 4108 ± 3102 ± 4103 ± 3
Body weight (g)378 ± 16359 ± 22362 ± 12356 ± 19
Kidney weight/body weight (g/kg)6.21 ± 0.536.34 ± 0.336.03 ± 0.266.28 ± 0.17
Total cholesterol (mg/dl)69 ± 4.5569.80 ± 4.3565.50 ± 4.3964.60 ± 4.11
Triglyceride (mg/dl)32.17 ± 3.2737.80 ± 5.6631.80 ± 5.7534.20 ± 5.04
Free fatty acid (mEq/l)0.24 ± 0.020.26 ± 0.020.26 ± 0.020.21 ± 0.02
Glucose (mg/dl)177.17 ± 5.36167.60 ± 7.03179.80 ± 6.93165.40 ± 7.12
Plasma creatinine (mg/dl)0.19 ± 0.010.17 ± 0.010.18 ± 0.010.16 ± 0.01
Creatinine clearance (ml/min)2.15 ± 0.312.45 ± 0.412.29 ± 0.352.64 ± 0.42
Plasma urea nitrogen (mg/dl)18.88 ± 0.6317.36 ± 0.6920.75 ± 0.8417.38 ± 0.78