High-Serum Angiopoietin-Like Protein 3 Levels Associated with Cardiovascular Outcome in Patients with Coronary Artery Disease

Table 3

Hazard ratio for cardiovascular events by multivariable Cox regression of angiopoietin-like protein 3 levels among the 90 patients with coronary artery disease.

ANGPTL3 (ng/mL)	Unadjusted		Model 1		Model 2		Model 3
	HR (95% CI)	value	HR (95% CI)	value	HR (95% CI)	value	HR (95% CI)	value
Per 1 ng/mL; ANGPTL3 increase	1.003 (1.002–1.004)	<0.001	1.003 (1.002–1.005)	<0.001	1.004 (1.003–1.006)	<0.001	1.003 (1.000–1.005)	0.026

Model 1 is adjusted for age, gender, and body mass index. Model 2 is adjusted for Model 1 variables and for diabetes mellitus, hypertension, fasting glucose, total cholesterol, triglyceride, low-density lipoprotein cholesterol, and estimated glomerular filtration rate. Model 3 is adjusted for Model 2 variables and for C-reactive protein, statin used, and severity of coronary artery disease. was considered statistically significant after Cox regression analysis. ANGPTL3, angiopoietin-like protein 3; HR, hazard ratio; and CI, confidence interval.