p38/JNK Is Required for the Proliferation and Phenotype Changes of Vascular Smooth Muscle Cells Induced by L3MBTL4 in Essential Hypertension

Figure 5

p38/JNK was required for VSMCs migration mediated by L3MBTL4. (a) Boyden chamber migration assays were performed, and the number of migratory VSMCs was assessed by crystal violet staining (n = 3). (b) Representative photomicrographs of cell morphology in the confluent cultured dishes of negative control, L3MBTL4 overexpressed cells, and cells treated with inhibitors. Scale bars are as shown. (c) Protein levels of SM-22 and OPN were measured by Western blot (n = 3). ; ; .

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