International Journal of Hypertension / 2020 / Article / Tab 2

Research Article

Genetic Predisposition and Salt Sensitivity in a Chinese Han Population: The EpiSS Study

Table 2

Association of the polygenic risk score with salt sensitivity.

Model AModel BModel C
OR (95% CI)OR (95% CI)OR (95% CI)

All
 PRS1.081 (1.035, 1.129)<0.0011.082 (1.036, 1.130)<0.0011.083 (1.037, 1.132)<0.001
 PRS tertiles
  1st vs 2nd1.694 (1.083, 2.652)0.0211.702 (1.085, 2.668)0.0201.725 (1.095, 2.716)0.019
  1st vs 3rd1.897 (1.205, 2.985)0.0061.913 (1.214, 3.015)0.0051.960 (1.233, 3.113)0.004
Hypertension
 PRS1.052 (0.987, 1.121)0.1171.054 (0.989, 1.124)0.1041.058 (0.991, 1.129)0.091
 PRS tertiles
  1st vs 2nd1.377 (0.714, 2.658)0.3401.370 (0.708, 2.651)0.3501.369 (0.703, 2.666)0.356
  1st vs 3rd1.582 (0.818, 3.057)0.1731.614 (0.832, 3.128)0.1571.654 (0.840, 3.260)0.146
Normotensives
 PRS1.106 (1.042, 1.174)0.0011.112 (1.048, 1.181)0.0011.109 (1.044, 1.179)0.001
 PRS tertiles
  1st vs 2nd2.096 (1.123, 3.912)0.0202.186 (1.162, 4.114)0.0152.179 (1.154, 4.116)0.016
  1st vs 3rd2.300 (1.219, 4.340)0.0102.378 (1.251, 4.522)0.0082.281 (1.189, 4.376)0.013

PRS, polygenic risk score. Model A: no variables were adjusted; model B: age and sex adjusted; model C: age, sex, smoking, BMI, dyslipidemia, and DM adjusted. ; .

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.