Research Article
Association between Plasma Urotensin II and Risk of Hypertension: Findings from a Prospective Study
Table 1
General characteristics of the 1819 participants by quartiles of levels of urotensin II at baseline.
| | | Quartiles of plasma urotensin II | value | | Quartile 1 (n = 453) | Quartile 2 (n = 456) | Quartile 3 (n = 455) | Quartile 4 (n = 455) |
| | Age, year | 52 (48–55) | 52 (47–55) | 52 (48–55) | 51 (17–55) | 0.386 | | Drinking, n (%) | 103 (22.7) | 96 (21.1) | 88 (19.3) | 91 (20.0) | 0.612 | | Smoking, n (%) | 135 (29.8) | 139 (30.5) | 143 (31.4) | 148 (32.5) | 0.827 | | Family history of HTN, n (%) | 187 (41.3) | 223 (48.9) | 201 (44.2) | 208 (45.7) | 0.135 | | Body mass index (kg/m2) | 22.5 (20.4–25.0) | 22.8 (20.2–25.1) | 22.4 (20.6–24.1) | 22.5 (20.5–24.6) | 0.699 | | Waist circumference (cm) | 80 (74–87) | 80 (73–86) | 80 (73–85) | 79 (72–85) | 0.100 | | Systolic blood pressure (mmHg) | 122 (115–130) | 121 (113–130) | 120 (112–128) | 121 (113–129) | 0.268 | | Diastolic blood pressure (mmHg) | 77 (72–82) | 77 (71–82) | 75 (69–81) | 76 (71–82) | 0.210 | | Fasting plasma glucose (mmol/L) | 4.9 (4.6–5.2) | 4.9 (4.5–5.2) | 4.8 (4.4–5.2) | 4.8 (4.4–5.2) | 0.043 | | Total cholesterol (mmol/L) | 4.5 (4.0–5.1) | 4.5 (3.9–5.1) | 4.5 (4.0–5.2) | 4.5 (3.9–5.1) | 0.830 | | Triglycerides (mmol/L) | 1.2 (0.9–1.9) | 1.3 (1.1–1.5) | 1.3 (0.9–1.9) | 1.3 (1.0–1.5) | 0.225 | | HDL-cholesterol (mmol/L) | 1.3 (1.1–1.5) | 1.3 (1.1–1.5) | 1.3 (1.1–1.5) | 1.3 (1.1–1.5) | 0.052 | | LDL-cholesterol (mmol/L) | 2.5 (2.0–3.0) | 2.4 (2.0–2.9) | 2.5 (2.0–3.0) | 2.5 (2.1–3.0) | 0.389 | | Endothelin-1 (pg/ml) | 1.21 (0.86–1.68) | 1.09 (0.80–1.54) | 1.04 (0.73–1.48) | 1.17 (0.81–1.57) | <0.0001 |
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Numerical variables were expressed as median (P25–P75); HTN: hypertension; HDL: high-density lipoprotein; LDL: low-density lipoprotein.
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