Research Article
Association between Plasma Urotensin II and Risk of Hypertension: Findings from a Prospective Study
Table 2
Comparison of baseline characteristics between the new cases of hypertension and the normotensive participants.
| | | Normotensive (n = 1096) | Hypertensive (n = 723) | value |
| | Age, year | 51 (47–54) | 53 (49–56) | <0.0001 | | Drinking, n (%) | 218 (19.9) | 160 (22.1) | 0.249 | | Smoking, n (%) | 351 (32.0) | 214 (29.6) | 0.274 | | Family history of HTN, n (%) | 465 (42.4) | 354 (49.0) | 0.006 | | Body mass index (kg/m2) | 21.9 (20.0–24.1) | 23.4 (21.1–25.7) | 0.699 | | Waist circumference (cm) | 76 (70–82) | 80 (73–86) | 0.100 | | Systolic blood pressure (mmHg) | 116 (109–126) | 128 (121–134) | <0.0001 | | Diastolic blood pressure (mmHg) | 74 (68–79) | 81 (76–85) | <0.0001 | | Fasting plasma glucose (mmol/L) | 4.8 (4.4–5.1) | 4.9 (4.6–5.3) | 0.043 | | Total cholesterol (mmol/L) | 4.4 (3.9–5.0) | 4.6 (4.1–5.3) | 0.830 | | Triglycerides (mmol/L) | 1.2 (0.9–1.7) | 1.4 (1.0–1.5) | 0.225 | | HDL-cholesterol (mmol/L) | 1.3 (1.1–1.5) | 1.3 (1.1–1.5) | 0.052 | | LDL-cholesterol (mmol/L) | 2.4 (2.0–3.0) | 2.5 (2.1–3.0) | 0.389 | | Endothelin-1 (pg/ml) | 1.12 (0.78–1.57) | 1.15 (0.80–1.53) | <0.0001 | | Urotensin II (pg/ml) | 83.37 (65.91–109.45) | 80.63 (64.11–105.62) | 0.203 |
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Numerical variables were expressed as median (P25–P75); HTN, hypertension; HDL, high-density lipoprotein; LDL, low-density lipoprotein.
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