Research Article

Association between Plasma Urotensin II and Risk of Hypertension: Findings from a Prospective Study

Table 5

Odds ratios of risk of hypertension associated with baseline urotensin II levels by strata of endothelin-1 levels.

Endothelin-1 <1.56 pg/ml (n = 1357)Endothelin-1 ≥1.56 pg/ml (n = 452)
Urotensin II < P75Urotensin II ≥ P75Urotensin II < P75Urotensin II ≥ P75

Model 1a1.0000.914 (0.707–1.180)1.0000.928 (0.595–1.449)
Model 2b1.0000.847 (0.635–1.129)1.0001.012 (0.609–1.684)
Model 3c1.0000.846 (0.634–1.129)1.0001.027 (0.615–1.712)
Model 4d1.0000.866 (0.647–1.159)1.0000.987 (0.587–1.660)

aAdjusted for age and sex; badjusted for age, sex, and systolic blood pressure at baseline; cadjusted for age, sex, systolic blood pressure, drinking, smoking, and family history of hypertension; dadjusted for age, sex, systolic blood pressure, drinking, smoking, family history of hypertension, body mass index, fasting plasma glucose, and total cholesterol.