Research Article
High Neutrophil-to-Lymphocyte Ratio Predicts Hemorrhagic Transformation in Acute Ischemic Stroke Patients Treated with Intravenous Thrombolysis
Table 1
Demographic and clinical characteristics of the study sample.
| | Characteristics | Mean (SD)/median (IQR)/n (%)
(n = 285) |
| | Age (years) | 62.3 ± 12.0 | | Men (n, %) | 201 (70.5%) | | Hypertension (n, %) | 211 (74.0%) | | Diabetes mellitus (n, %) | 79 (27.7%) | | Smokers/ex-smokers (n, %) | 102 (35.8%) | | Atrial fibrillation (n, %) | 67 (23.5%) | | Previous stroke (n, %) | 52 (18.2%) | | PAT (n, %) | 23 (8.1%) | | POAT (n, %) | 8 (2.8%) | | Time of poststroke antiplatelet therapy | | | Before MRI scan (n, %) | 212 (74.4%) | | After MRI scan (n, %) | 66 (23.2%) | | No antiplatelet therapy | 7 (2.4%) | | OTT (minutes) | 200.4 ± 55.9 | | NIHSS score on admission | 7 (4–10) | | Platelet counts (109/L) | 214.0 ± 55.9 | | WBC counts (109/L) | 8.4 ± 2.9 | | Neutrophil counts (109/L) | 5.8 ± 2.8 | | Lymphocyte counts (109/L) | 1.9 ± 0.9 | | NLR | 2.7 (1.8–4.3) | | High NLR (n, %) | 71 (24.9%) | | Uric acid (mmol/L) | 390.1 ± 108.6 | | BG on admission (mmol/L) | 7.5 ± 3.2 | | SBP on admission (mmHg) | 157.4 ± 24.8 | | DUB on admission (mmHg) | 91.4 ± 16.5 | | SVD burden | 1 (0–2) | | Hemorrhagic transformation (n, %) | 72 (25.3%) | | HI1 | 44 (15.4%) | | HI2 | 21 (7.4%) | | PH1 | 4 (1.4) | | PH2 | 3 (1.1%) | | sHT (n, %) | 3 (1.1%) |
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BG = blood glucose; DBP = diastolic blood pressure; HI = hemorrhagic infarct; NIHSS=National Institutes of Health Stroke Scale; NLR=neutrophil-to-lymphocyte ratio; OTT = onset-to-treatment time; PAT = previous antiplatelet therapy; PH = parenchymatous hemorrhage; POAT = previous oral anticoagulant therapy; SBP = systolic blood pressure; sHT = symptomatic hemorrhagic transformation; SVD = small vessel disease; WBC = white blood cell median (25Q–75Q). |
