Research Article
Modification of Platelet Count on the Association between Homocysteine and Blood Pressure: A Moderation Analysis in Chinese Hypertensive Patients
Table 1
Clinical characteristics of study participants according to platelet count.
| Characteristics | Low platelet count (<210 × 109/L) | High platelet count (≥210 × 109/L) | |
| No. of participants | 21,980 | 8,389 | | Age (years) | 63.3 ± 7.1 | 61.7 ± 7.2 | <0.001 | Sex, men (%) | 11,087 (50.44) | 3,516 (41.91) | <0.001 | Antihypertensive medication, n (%) | 18,897 (85.97) | 7,312 (87.16) | 0.007 | Body mass index (kg/m2) | 24.71 ± 3.36 | 25.08 ± 3.31 | <0.001 | Fasting glucose (mmol/L) | 5.92 ± 1.48 | 5.94 ± 1.46 | 0.252 | Total cholesterol (mmol/L) | 4.82 ± 1.01 | 5.10 ± 1.04 | <0.001 | Triglycerides (mmol/L) | 1.80 ± 1.40 | 1.96 ± 1.43 | <0.001 | LDL-C (mmol/L) | 2.78 ± 0.81 | 3.06 ± 0.84 | <0.001 | HDL-C (mmol/L) | 1.49 ± 0.48 | 1.47 ± 0.45 | <0.001 | Creatinine (mmol/L) | 73.37 ± 36.96 | 69.57 ± 30.47 | <0.001 | Systolic blood pressure (mmHg) | 143.8 ± 17.6 | 144.6 ± 17.5 | <0.001 | Diastolic blood pressure (mmHg) | 83.0 ± 10.5 | 84.0 ± 10.7 | <0.001 | Log-Hcy | 2.40 ± 0.49 | 2.41 ± 0.48 | 0.037 | Platelet consumption | | | | Mean platelet volume (fL) | 10.10 ± 1.75 | 8.87 ± 1.45 | <0.001 | Platelet crit (%) | 0.1559 ± 0.0350 | 0.2192 ± 0.0450 | <0.001 | Platelet distribution width (%) | 16.36 ± 0.93 | 15.90 ± 1.08 | <0.001 |
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All results are expressed in mean ± SD unless otherwise noted. LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Log-Hcy: log-transformed homocysteine.
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