Modification of Platelet Count on the Association between Homocysteine and Blood Pressure: A Moderation Analysis in Chinese Hypertensive Patients

Table 2

The association between serum homocysteine and blood pressure according to platelet count.

Subgroups	z-transformed SBP			z-transformed DBP
	β (SE)		for difference in β	β (SE)		for difference in β
Total participants	0.017 (0.013)	0.181	—	0.078 (0.012)	<0.001	—
Subgroup by quartiles of platelet count
Q1 (<146 × ×10^9/L)	−0.010 (0.025)	0.683	0.249	0.108 (0.024)	<0.001	0.003
Q2 (146–178 × 10^9/lL)	0.053 (0.026)	0.044		0.098 (0.025)	<0.001
Q3 (179–213 × 10^9/lL)	0.044 (0.026)	0.091		0.058 (0.025)	0.019
Q4 (≥214 × 10^9/L)	−0.027 (0.026)	0.297		0.039 (0.025)	0.119
Subgroup by platelet count referring to CSPPT
Platelet count <210 × 10^9/L	0.026 (0.015)	0.079	0.017	0.092 (0.014)	<0.001	0.004
Platelet count ≥210 × 10^9/L	−0.017 (0.025)	0.502		0.035 (0.024)	0.144

The increase of z-transformed SBP (β) per unit increment of log-transformed homocysteine and its significance test (); the increase of z-transformed DBP (β) per unit increment of log-transformed homocysteine and its significance test (); the significance test of the difference in the regression coefficients between the two subgroups.