Assessment of Plasma Sodium to Potassium Ratio, Renal Function, Markers of Oxidative Stress, Inflammation, and Endothelial Dysfunction in Nigerian Hypertensive Patients

Table 2

Biomarkers of renal function, plasma sodium-potassium ratio, and inflammatory biomarkers between hypertensive and control volunteers.

Parameter	Hypertension (n = 323) mean ± SD	Control (n = 225) mean ± SD	value
Uric acid (μmol/l)	396.3 ± 121.6	402.9 ± 129.2	0.7600
Na^+(mmol/L)	136.86 ± 5.95	132.22 ± 4.54	<0.001
K^+(mmol/L)	3.38 ± 0.49	3.50 ± 0.58	0.0100
Plasma Na^+/K^+	41.32 ± 6.17	38.66 ± 5.90	<0.001
HCO3^− (mmol/L)	19.58 ± 3.57	22.93 ± 3.23	<0.001
Urea (mmol/L); (interquartile range)	3.83; (3.16–4.66)	3.66; (3.16–4.16)	0.0495
Creatinine (μmol/L); (interquartile range)	79.56; (63.65–97.24)	79.56; (70.72–88.40)	0.9693
eGFR (ml/min/1.73 m^2); (interquartile range)	88.019; (74.85–108.26)	92.399; (77.41–105.42)	0.2560
hs-CRP (μg/mL); (interquartile range)	10.07; (4.12–12.52)	1.24; (0.76–2.20)	<0.001
CAT (μmol/ml/min); (interquartile range)	206; (148–297.14)	107.20; (75.44–134)	<0.001

Significant probability ().