Research Article

Assessment of Plasma Sodium to Potassium Ratio, Renal Function, Markers of Oxidative Stress, Inflammation, and Endothelial Dysfunction in Nigerian Hypertensive Patients

Table 3

Biomarkers of oxidative stress and endothelial function of hypertensive and control volunteers.

ParameterHypertension (n = 320) median (IQR)Control (n = 225) median (IQR) value

GSH (μmol/ml)
(interquartile range)
6.34
(3.99–9.02)
9.66
(8.23–11.55)
<0.001
MDA (μmol/ml)
(interquartile range)
10.69
(6.27–11.85)
3.69
(2.23–11.55)
<0.001
NO (μmol/dl)
(interquartile range)
10.78
(7.58–16.12)
34.68
(31.07–37.53)
<0.001
SOD (μmol/ml/min)
(interquartile range)
62.93
(30.40–87.87)
101.34
(92.08–107.69)
<0.001
CAT (μmol/ml/min)
(interquartile range)
191.35
(93.11–310.09)
431.82
(274.32–517.67)
<0.001

Significant probability (); IQR: interquartile range.