Cross-Sectional Relationship between Carotid-Femoral Pulse Wave Velocity and Biomarkers in Vascular-Related Diseases

Table 2

Clinical characteristics in different groups.

Characteristics	Non-CHD group (N = 425)	CHD group (N = 231)
Age (year）	58.3 ± 10.7	65.3 ± 11.3	<0.001
Male/female	168/257	104/127	0.173
Hypertension (%)	49.8	73.5	<0.001
DM (%)	18.6	32.5	<0.001
CCB (%)	13.2	29.4	<0.001
ACEI/ARB (%)	12.7	28.1	<0.001
B-blocker (%)	7.8	43.6	<0.001
Antidiabetic agent (%)	9.2	22.9	<0.001
Lipid-lowering	23.1	46.3	<0.001
Agent (%)
Smoking (%)	32.2	36.4	0.285
BMI (kg/m^2)	25.18 ± 3.46	25.94 ± 3.57	0.008
CFPWV (m/s)	10.72 ± 2.37	11.63 ± 2.52	<0.001
RABI	1.125 ± 0.099	1.091 ± 0.108	<0.001
LABI	1.116 ± 0.107	1.099 ± 0.119	0.076
SBP (mmHg)	136.6 ± 19.3	141.2 ± 20.0	0.004
DBP (mmHg)	84.1 ± 11.0	83.6 ± 11.8	0.574
Pulse pressure (mmHg)	52.4 ± 13.4	57.6 ± 15.2	<0.001
FPG (mmol/L)	5.82 ± 1.32	6.21 ± 2.02	0.010
UA (μmol/L)	304.6 ± 76.5	321.5 ± 83.3	0.010
Creatinine (μmol/L)	65.3 ± 19.3	67.9 ± 18.9	0.089
TC (mmol/L)	5.02 ± 1.17	4.52 ± 1.10	<0.001
HDL-C (mmol/L)	1.28 ± 0.33	1.14 ± 0.27	<0.001
LDL-C (mmol/L)	3.11 ± 0.92	2.65 ± 0.82	<0.001
TG (mmol/L)	1.77 ± 1.40	1.86 ± 2.05	0.496
HCY (μmol/L)	12.73 ± 7.18	15.58 ± 7.68	<0.001
Log NT-proBNP	1.89–2.31	1.99–.57	<0.001
Log UAE	0.40–0.91	0.47–0.99	0.028

BMI, body mass index; CFPWV, carotid-femoral pulse wave velocity; RABI, right ankle brachial index; LABI, left ankle brachial index; SBP, systolic blood pressure; DBP, diastolic blood pressure; FPG, fasting plasma glucose; UA, uric acid; TC, cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglycerides; HCY, homocysteine; UAE, urine albumin (microalbumin) excretion; CCB, calcium channel blocker; ACEI, angiotensin-converting enzyme inhibitors; ARB, angiotensin receptor blocker.