Long-Term Risk of Progression to Sustained Hypertension in White-Coat Hypertension with Normal Night-Time Blood Pressure Values
Table 2
Blood pressure data.
NT (n = 434)
WCHT untreated (n = 399)
WCHT treated (n = 156)
≤
In office-blood pressure and heart rate
SBPc baseline (mm Hg)
128 ± 8
151 ± 11
150 ± 10
0.001
DBPc baseline (mm Hg)
84 ± 9
91 ± 10
90 ± 10
0.001
HRc baseline (b/min)
78 ± 10
81 ± 9
80 ± 10
0.710
SBPc final (mm Hg)
131 ± 8.9
146 ± 11
143 ± 10
0.001
DBPc final (mm Hg)
86 ± 9
88 ± 10
86 ± 10
0.001
HRc final (b/min)
79 ± 11
80 ± 9
79 ± 11
0.261
Delta SBPc (mm hg)
3.0 ± 2.1
−3.9 ± 3.0
−6.1 ± 5.9
0.001
Delta DBPc (mm hg)
2.8 ± 3.7
−2.6 ± 2.7
−4.2 ± 2.1
0.001
24 h-blood pressure and heart rate
SBP 24 h baseline (mm Hg)
120 ± 7
123 ± 5
122 ± 5
0.001
DBP 24 h baseline (mm Hg)
73 ± 7
75 ± 7
74 ± 7
0.001
HR 24 h baseline (b/min)
74 ± 9
73 ± 10
72 ± 10
0.159
SBP 24 h final (mm Hg)
122 ± 7
125 ± 6
123 ± 6§
0.001
DBP 24 h final (mm Hg)
74 ± 6
78 ± 7
73 ± 6§
0.001
HR 24 h final (b/min)
73 ± 8
72 ± 9
72 ± 9
0.311
Delta SBP24 h (mm Hg)
2.4 ± 3.1
2.9 ± 4.1
0.7 ± 1.9§
0.001
Delta DBP24 h (mm Hg)
1.1 ± 2.4
1.2 ± 5.4
0.23 ± 1.4§
0.001
Daytime-blood pressure and heart rate
SBP daytime baseline (mm Hg)
124 ± 8
126 ± 6
126 ± 5
0.01
DBP daytime baseline (mm Hg)
77 ± 7
79 ± 7
78 ± 7
0.01
HR daytime baseline (b/min)
77 ± 10
76 ± 11
75 ± 10
0.170
SBP daytime final (mm Hg)
126 ± 8
129 ± 7
127 ± 6
0.001
DBP daytime final (mm Hg)
78 ± 7
80 ± 7
77 ± 7
0.01
HR daytime final (b/min)
76 ± 9
77 ± 10
74 ± 10
0.231
Delta SBP daytime (mm Hg)
2.2 ± 3.1
2.5 ± 6.0
0.7 ± 2.8§
0.001
Delta DBP daytime (mm Hg)
1.0 ± 2.5
1.5 ± 6.1
0.4 ± 1.8§
0.001
Nighttime-blood pressure and heart rate
SBP nighttime baseline (mm Hg)
110 ± 8
111 ± 7
112 ± 8
0.01
DBP nighttime baseline (mm Hg)
65 ± 7
66 ± 7
66 ± 7
0.01
HR nighttime baseline (b/min)
66 ± 9
65 ± 9
66 ± 10
0.644
SBP nighttime final (mm Hg)
112 ± 9
114 ± 8
112 ± 8
0.013
DBP nighttime final (mm Hg)
66 ± 7
67 ± 8
65 ± 7
0.128
HR nighttime final (b/min)
67 ± 9
66 ± 9
67 ± 10
0.233
Delta SBP nighttime (mm Hg)
1.7 ± 3.0
2.1 ± 9.0
0.5 ± 3.0§
0.001
Delta DBP nighttime (mm Hg)
0.6 ± 4.5
0.9 ± 6.9
0.7 ± 2.8
0.01
Nighttime BP fall (%)
Nighttime fall SBP baseline
10.7 ± 5.9
12.1 ± 6.5
12.7 ± 6.8
0.01
Nighttime fall DBP baseline
15.3 ± 7.4
15.9 ± 7.6
16.3 ± 7.6
0.259
Nighttime fall SBP final
10.3 ± 4.9
11.9 ± 5.8
12.0 ± 5.9
0.01
Nighttime fall DBP final
15.1 ± 6.5
15.3 ± 6.8
15.4 ± 6.8
0.232
NT, normotensives; WCHT, white-coat hypertensives; SBPc, office systolic BP; DBPc, office diastolic BP; HRc, office heart rate; Delta, difference between baseline and the end of the follow-up (final). Post hoc analysis: vs. NT; different from WCHT treated; § WCHT treated vs. WCTH untreated.
