Association between Single Nucleotide Polymorphisms in Cardiovascular Developmental Critical Genes and Hypertension: A Propensity Score Matching Analysis
Table 2
The distribution of SNP genotypes between the control and hypertension groups.
Variables
Control
Hypertension
value
Ref. homo
Hetero
Alt. homo
Ref. homo
Hetero
Alt. homo
rs2277538 (DLL4)
189 (84.0)
34 (15.1)
2 (0.9)
183 (81.3)
40 (17.8)
2 (0.9)
0.75
rs3212278 (DLL4)
94 (41.8)
115 (51.1)
16 (7.1)
113 (50.2)
91 (40.4)
21 (9.3)
0.07
rs7667298 (KDR)
90 (40.0)
98 (43.6)
37 (16.4)
88 (39.1)
113 (50.2)
24 (10.7)
0.15
rs2305948 (KDR)
165 (73.3)
59 (26.2)
1 (0.4)
159 (70.7)
63 (28.0)
3 (1.3)
0.54
rs13109660 (KDR)
103 (45.8)
97 (43.1)
25 (11.1)
105 (46.7)
100 (44.4)
20 (8.9)
0.73
rs7671745 (KDR)
98 (43.6)
98 (43.6)
29 (12.9)
99 (44.0)
93 (41.3)
33 (14.7)
0.82
rs3124591 (NOTCH1)
201 (89.3)
24 (10.7)
0 (0.0)
200 (88.9)
25 (11.1)
0 (0.0)
0.88
rs9818496 (PDCD10)
167 (74.2)
57 (25.3)
1 (0.4)
170 (75.6)
54 (24.0)
1 (0.4)
0.95
rs3804610 (PDCD10)
168 (74.7)
56 (24.9)
1 (0.4)
172 (76.4)
52 (23.1)
1 (0.4)
0.91
rs6784267 (PDCD10)
90 (40.0)
106 (47.1)
29 (12.9)
95 (42.2)
96 (42.7)
34 (15.1)
0.60
rs833061 (VEGFA)
127 (56.4)
73 (32.4)
25 (11.1)
133 (59.1)
81 (36.0)
11 (4.9)
0.04
rs10434 (VEGFA)
142 (63.1)
77 (34.2)
6 (2.7)
133 (59.1)
79 (35.1)
13 (5.8)
0.24
rs833069 (VEGFA)
86 (38.2)
105 (46.7)
34 (15.1)
72 (32.0)
108 (48.0)
45 (20.0)
0.25
rs3025010 (VEGFA)
117 (52.0)
83 (36.9)
25 (11.1)
134 (59.6)
79 (35.1)
12 (5.3)
0.03
rs3025053 (VEGFA)
168 (74.4)
53 (23.6)
4 (1.8)
161 (71.6)
59 (26.2)
5 (2.2)
0.75
rs699947 (VEGFA)
127 (56.4)
73 (32.4)
25 (11.1)
153 (59.1)
93 (36.0)
12 (4.9)
0.04
rs2146323 (VEGFA)
133 (59.1)
71 (31.6)
21 (9.3)
139 (61.8)
73 (32.4)
13 (5.8)
0.36
rs3025035 (VEGFA)
158 (70.2)
60 (26.7)
7 (3.1)
155 (68.9)
63 (28.0)
7 (3.1)
0.95
rs3025030 (VEGFA)
152 (67.6)
69 (30.7)
4 (1.8)
143 (63.6)
78 (34.7)
4 (1.8)
0.66
Ref. homo: reference homogeneous major allele genotype; hetero: heterogeneous genotype; alt. homo: altered homogeneous minor allele genotype. values have significance.
