Association between Single Nucleotide Polymorphisms in Cardiovascular Developmental Critical Genes and Hypertension: A Propensity Score Matching Analysis
Table 3
The distribution of SNP allele frequencies in control and hypertension groups.
Variables
Control
Hypertension
value
Ref.
Alt.
Ref.
Alt.
rs2277538 (DLL4)
412 (91.6)
38 (8.4)
406 (90.2)
44 (9.8)
0.49
rs3212278 (DLL4)
303 (67.3)
147 (32.7)
317 (70.4)
133 (29.6)
0.31
rs7667298 (KDR)
278 (61.8)
172 (38.2)
289 (64.2)
161 (35.8)
0.45
rs2305948 (KDR)
389 (86.4)
61 (13.6)
381 (84.7)
69 (15.3)
0.45
rs13109660 (KDR)
303 (67.3)
147 (32.7)
310 (68.9)
140 (31.1)
0.62
rs7671745 (KDR)
294 (65.3)
156 (34.7)
291 (64.7)
159 (35.3)
0.83
rs3124591 (NOTCH1)
402 (89.3)
48 (10.7)
400 (88.9)
50 (11.1)
0.83
rs9818496 (PDCD10)
391 (86.9)
59 (13.1)
394 (87.6)
56 (12.4)
0.77
rs3804610 (PDCD10)
392 (87.1)
58 (12.9)
396 (88.0)
54 (12.0)
0.69
rs6784267 (PDCD10)
286 (63.6)
164 (36.4)
286 (63.6)
164 (36.4)
1.00
rs833061 (VEGFA)
327 (72.7)
123 (27.3)
347 (77.1)
103 (22.9)
0.12
rs10434 (VEGFA)
361 (80.2)
89 (19.8)
345 (76.7)
105 (23.3)
0.20
rs833069 (VEGFA)
277 (61.6)
173 (38.4)
252 (56.0)
198 (44.0)
0.09
rs3025010 (VEGFA)
317 (70.4)
133 (29.6)
347 (77.1)
103 (22.9)
0.02
rs3025053 (VEGFA)
389 (86.4)
61 (13.6)
381 (84.7)
69 (15.3)
0.45
rs699947 (VEGFA)
327 (72.7)
123 (27.3)
333 (74.0)
117 (26.0)
0.65
rs2146323 (VEGFA)
337 (74.9)
113 (25.1)
351 (78.0)
99 (22.0)
0.27
rs3025035 (VEGFA)
376 (83.6)
74 (16.4)
373 (82.9)
77 (17.1)
0.79
rs3025030 (VEGFA)
373 (82.9)
77 (17.1)
366 (81.3)
84 (18.6)
0.54
Ref.: reference allele; alt.: altered (minor) allele. values have significance.
