Association between rs20456 and rs6930913 of Kinesin-Like Family 6 and Hypertension in a Chinese Cohort

Table 2

General characteristics of all individuals.

Characteristics	Cases (n = 382)	Controls (n = 378)	P value	P value
Gender (male/female)	220/162	168/210	0.001
Age (years)	58.67 ± 8.62	62.43 ± 4.88	<0.0001
SBP (mmHg)	179.69 ± 19.21	120.54 ± 10.42	<0.0001
DBP (mmHg)	108.74 ± 9.00	74.85 ± 6.81	<0.0001
Smoking (%)	184 (48.2%)	206 (54.5%)	0.082	<0.0001
Having	184	206
Never	198	172
BMI (kg/m^2)	25.08 ± 3.44	22.60 ± 3.55	<0.0001	<0.0001
LDL-C (mmol/l)	3.31 ± 2.12	2.85 ± 0.74	<0.0001	<0.0001
TG (mmol/l)	1.64 ± 1.66	1.67 ± 1.14	0.809
Cr (µmol/l)	86.72 ± 13.68	52.30 ± 11.19	<0.0001	<0.0001
FBG (mmol/l)	5.63 ± 1.77	5.73 ± 1.59	0.432
Na^+ (mmol/l)	143.54 ± 2.22	142.45 ± 2.42	<0.0001	<0.0001
K^+ (mmol/l)	4.27 ± 0.51	4.23 ± 0.35	0.254

BMI, body mass index; Cr, serum creatinine; DBP, diastolic blood pressure; FBG, fasting plasma glucose; K⁺, potassium; LDL-C, low-density lipoprotein cholesterol; Na⁺, sodium; SBP, systolic blood pressure; TG, triglyceride; smoking (having), current or past smoking; smoking (never), never smoked. Statistically significant differences () are marked in bold. Adjusting for gender and age.