Association between rs20456 and rs6930913 of Kinesin-Like Family 6 and Hypertension in a Chinese Cohort
Table 4
Gene-environmental interactions on the risk of hypertension.
Smoking
BMI (kg/m2)
Ever/never
P
≥25/<25
P
rs20456
CC
—
—
—
—
TC
11.941 (1.181–120.777)
0.036
0.160 (0.017–1.537)
0.112
TT
20.234 (1.537–266.334)
0.022
0.081 (0.006–1.152)
0.064
Dominant (TT + CT/CC)
6.895 (1.014–46.862)
0.048
0.151 (0.021–1.075)
0.059
Recessive (TT/CT + CC)
3.773 (0.592–24.032)
0.160
0.493 (0.081–2.998)
0.443
rs6930913
CC
—
—
—
—
CT
0.112 (0.012–1.014)
0.051
0.812 (0.112–5.878)
0.836
TT
10.303 (0.854–124.331)
0.066
7.846 (0.690–89.207)
0.097
Dominant (TT + CT/CC)
16.290 (2.193–120.980)
0.006
1.367 (0.235–7.946)
0.728
Recessive (TT/CT + CC)
16.500 (2.218–122.725)
0.006
6.608 (0.987–44.234)
0.052
Adjusting for gender, age, low-density lipoprotein cholesterol, and creatinine. BMI, body mass index. Statistically significant differences () are marked in bold.
