Research Article

Sympathetic Nerve Activity and Baroreflex are Strongly Altered in a Context of Severe Hypertension Using the Spontaneously Hypertensive Rat Model Associated with Chronic Reduction of Nitric Oxide

Table 2

Bezold–Jarisch reflex data.

BasalCPBG 1 µg/kgCPBG 3 µg/kgCPBG 20 µg/kg

RSNA, %WKY n = 7−58 ± 5−65 ± 5−67 ± 5
SHR n = 5−70 ± 6−76 ± 4−73 ± 6
SHRLN n = 7−67 ± 10−78 ± 4−81 ± 4

MBP, mmHgWKY113 ± 4−19 ± 4−30 ± 7−49 ± 4
SHR176 ± 8−46 ± 4−72 ± 7−80 ± 8
SHRLN168 ± 14−32 ± 6−43 ± 7#−50 ± 9#

HR, bpmWKY408 ± 15−49 ± 10−107 ± 15−257 ± 32
SHR357 ± 20−108 ± 35−179 ± 32−257 ± 17
SHRLN354 ± 12−57 ± 16−116 ± 31−142 ± 34#

2-way ANOVA and Tukey’s multiple comparison test, . SHR or SHRLN versus WKY. #SHRLN versus SHR.