Sympathetic Nerve Activity and Baroreflex are Strongly Altered in a Context of Severe Hypertension Using the Spontaneously Hypertensive Rat Model Associated with Chronic Reduction of Nitric Oxide
Table 2
Bezold–Jarisch reflex data.
Basal
CPBG 1 µg/kg
CPBG 3 µg/kg
CPBG 20 µg/kg
RSNA, %
WKY n = 7
—
−58 ± 5
−65 ± 5
−67 ± 5
SHR n = 5
—
−70 ± 6
−76 ± 4
−73 ± 6
SHRLN n = 7
—
−67 ± 10
−78 ± 4
−81 ± 4
MBP, mmHg
WKY
113 ± 4
−19 ± 4
−30 ± 7
−49 ± 4
SHR
176 ± 8
−46 ± 4
−72 ± 7
−80 ± 8
SHRLN
168 ± 14
−32 ± 6
−43 ± 7#
−50 ± 9#
HR, bpm
WKY
408 ± 15
−49 ± 10
−107 ± 15
−257 ± 32
SHR
357 ± 20
−108 ± 35
−179 ± 32
−257 ± 17
SHRLN
354 ± 12
−57 ± 16
−116 ± 31
−142 ± 34#
2-way ANOVA and Tukey’s multiple comparison test, . SHR or SHRLN versus WKY. #SHRLN versus SHR.