Relationship between Insulin Secretion and Arterial Stiffness in Essential Hypertension

Table 3

Multiple linear regression analysis showing variables independently associated with baPWV.

Variables	Model 1			Model 2			Model 3
	β	95% CI	P value	β	95% CI	P value	β	95% CI	P value
0 h PG (mmol/L)	0.055	−9.568–−67.659	0.14	0.021	−24.495–−47.317	0.533	0.037	−13.541–−53.059	0.244
2 h PG (mmol/L)	0.032	−8.266–−21.300	0.387	0.039	−5.763–−21.586	0.256	0.035	−5.553–−19.844	0.270
Δ PG (mmol/L)	0.012	−13.292–−18.549	0.746	0.033	−7.477–−22.005	0.334	0.022	−8.710–−18.532	0.479
0 h C-peptide (ng/ml)	−0.062	−44.579–−3.651	0.096	0.037	−10.729–−35.498	0.293	0.091	6.782–−53.487	0.012
2 h C-peptide (ng/ml)	0.077	0.389–−12.906	0.037	0.077	0.865–−12.442	0.024	0.089	2.237–−13.094	0.006
Δ C-peptide (ng/ml)	0.106	3.323–−17.558	0.004	0.078	1.069–−14.318	0.023	0.078	1.534–−13.777	0.014

Model 1: not adjusted. Model 2: adjusted for age and sex. Model 3: adjusted for age, sex, current smoking, BMI, HDL-C, mean 24 h SBP, and TG. CI, confidence interval; baPWV, brachial-ankle pulse wave velocity; PG, plasma glucose; BMI, body mass index; HDL-C, high-density lipoprotein cholesterol; SBP, systolic blood pressure; TG, triglycerides.