Genetic Variation in Taste Receptor Genes (SCNN1B, TRPV1) and Its Correlation with the Perception of Saltiness in Normotensive and Hypertensive Adults

Table 5

Genotypes and allele distribution in normotensive and hypertensive groups.

Gene	Variant	Genotype	N (%)	MAF	HWE value^a
Normotensive group
SCNN1B	rs239345	AA	6 (4.7)	0.24	0.537
		AT	49 (38.3)
		TT	73 (57.0)
	rs3785368	AA	4 (3.1)	0.16	0.557
		AG	32 (25.0)
		GG	92 (71.9)
TRPV1	rs8065080	CC	17 (13.3)	0.32	0.153
		CT	49 (38.3)
		TT	62 (48.4)
	rs4790522	AA	23 (18.0)	0.43	0.819
		AC	64 (50.0)
		CC	41 (32.0)
Hypertensive group
SCNN1B	rs239345	AA	15 (12.0)	0.35	0.957
		AT	57 (45.6)
		TT	53 (42.4)
	rs3785368	AA	3 (2.4)	0.12	0.250
		AG	23 (18.4)
		GG	99 (79.2)
TRPV1	rs8065080	CC	9 (7.2)	0.22	0.094
		CT	36 (28.8)
		TT	80 (64.0)
	rs4790522	AA	30 (24.0)	0.49	0.926
		AC	63 (50.4)
		CC	32 (25.6)

HWE: Hardy–Weinberg Equilibrium, MAF: minor allele frequency. ^aChi-square test.