The Association between Gly460Trp-Polymorphism of Alpha-Adducin 1 Gene (ADD1) and Arterial Hypertension Development in Ukrainian Population

Table 10

Association analysis between ADD1 rs4961-polymorphism and salt-sensitivity occurrence among females.

Model of inheritance	Рс	ORc (95% CI)	Pa^2	ORa (95% CI)
Dominant	0.019	3.864 (1.251–11.935)	0.016 (0.258)	5.213 (1.36–19.99)
Overdominant	0.061	2.957 (0.951–9.191)	0.053 (0.377)	3.714 (0.983–14.03)
Additive^1	0.04	3.312 (1.058–10.369)	0.03 (0.3)	4.445 (1.151–17.165)

P_ccrude value; OR_ccrude odds ratio; P_a value adjusted for age, smoking habit, AH presence in family history, and AH grade; OR_aodds ratio adjusted for age, smoking habit, AH presence in family history, and AH grade; 95% CI95% confidence interval. 1upper row: comparison between GT and TT genotypes; lower row: comparison between TT and GG genotypes. 2: value adjusted for BMI is shown in parentheses.