The Association between Gly460Trp-Polymorphism of Alpha-Adducin 1 Gene (ADD1) and Arterial Hypertension Development in Ukrainian Population

Table 8

Association analysis between ADD1 rs4961-polymorphism and salt-sensitivity occurrence.

Model of inheritance	Pc	ORc (95% CI)	Pa^2	ORa (95% CI)
Dominant	0.013	3.201 (1.285–7.977)	0.018 (0.443)	3.141 (1.221–8.08)
Overdominant	0.047	2.557 (1.013–6.455)	0.054 (0.574)	2.562 (0.983–6.675)
Additive^1	0.033	2.774 (1.083–6.952)	0.038 (0.509)	2.756 (1.056–7.196)

P_ccrude value; OR_ccrude odds ratio; P_a value adjusted for age, smoking habit, AH presence in family history, and AH grade; OR_a odds ratio adjusted for age, smoking habit, AH presence in family history, and AH grade; 95% CI95% confidence interval. 1upper row: comparison between GT and TT genotypes; lower row: comparison between TT and GG genotypes. 2: value adjusted for sex and BMI is shown in parentheses.