Higher Apnea-Hypopnea Index (AHI) and Oxygen Desaturation Index (ODI) Were Independently Associated with Increased Risks of Hypertension in Patients with T2DM: A Cross-Sectional Study

Table 3

Unadjusted and adjusted odds ratios (ORs) with associated 95% confidence interval (CI) for hypertension in patients with T2DM.

Variables	Unadjusted OR			Adjusted OR^∗
	OR	95% CI	value	OR	95% CI	value
AHI (events/h)	1.040	1.024–1.055	<0.001	1.026	1.008–1.044	0.004
REM-AHI (events/h)	1.019	1.004–1.034	0.012	1.009	0.993–1.026	0.260
NREM-AHI (events/h)	1.040	1.025–1.055	<0.001	1.026	1.009–1.044	0.003
OSAS categories
None	1.000			1.000
Mild	1.914	1.027–3.564	0.041	1.360	0.669–2.765	0.396
Moderate	3.358	1.736–6.497	<0.001	1.656	0.765–3.585	0.200
Severe	6.296	3.159–12.548	<0.001	3.626	1.609–8.172	0.002
Trend test			<0.001			0.002
ODI
ODI (events/h)	1.010	1.004–1.016	0.001	1.005	1.000–1.010	0.040
Tertiles of ODI
Tertile 2 vs. tertile 1	2.674	1.464–4.885	0.001	1.730	0.867–3.452	0.120
Tertile 3 vs. tertile 1	5.024	2.750–9.178	<0.001	2.452	1.222–4.921	0.012
Trend test			<0.001			0.016
Lowest SaO2 (%)	0.969	0.947–0.991	0.005	0.980	0.995–1.005	0.115

^∗OR was adjusted for age, sex, current smoking, regular drinking, BMI, WC, diabetes duration, total cholesterol, HDL-cholesterol, triglyceride, LDL-cholesterol, HbA1c, and eGFR. AHI, apnea-hypopnea index; CI, confidence interval; NREM, nonrapid eye movement; ODI, oxygen desaturation index; OR, odds ratio; OSAS, obstructive sleep apnea syndrome; REM, rapid eye movement; SaO₂, arterial oxygen saturation; T2DM, type 2 diabetes mellitus.