Disturbances of the Gut Microbiota, Sleep Architecture, and mTOR Signaling Pathway in Patients with Severe Obstructive Sleep Apnea-Associated Hypertension

Table 1

Participant characteristics.

	Non-OSA	OSA	value
	(n = 12)	(n = 60)
Gender (male/female)	6/6	57/3	NA^a
Age (years, mean ± SD)	38.25 ± 8.06	42.12 ± 7.63	0.117
Height (cm)	165.25 ± 8.41	168.28 ± 6.81	0.180
Weight (kg)	65.38 ± 8.96	81.11 ± 12.01	<0.001
Body mass index (kg m^−2)	23.81 ± 2.59	28.49 ± 3.76	<0.001
Waist circumference (cm)	80.00 ± 6.73	97.32 ± 8.04	<0.001
Hip circumference (cm)	94.42 ± 7.03	100.89 ± 6.09	0.002

^aN/A: not analyzed. Non-OSA: subjects with apnea-hypopnea index (AHI) ≤5 without hypertension; OSA: patients with severe OSA (AHI ≥30) with/without hypertension. The statistical analysis was performed with a t-test. values < 0.05 were considered significant.