Research Article

Disturbances of the Gut Microbiota, Sleep Architecture, and mTOR Signaling Pathway in Patients with Severe Obstructive Sleep Apnea-Associated Hypertension

Table 3

Top 10 differentially expressed mRNAs in severe-OSA with HTN patients compared with non-OSA without hypertension subjects.

Upregulated mRNAsDownregulated mRNAs
Transcript ID valuelog2FoldChangeTranscript ID valuelog2FoldChange
(Ensembl_Gene_ID)(Ensembl_Gene_ID)

ENSG000001235051.09E − 0.50.871616484ENSG000002683508.82E − 0.8−1.315999106
ENSG000002423711.86E − 0.51.397821661ENSG000001495911.17E − 0.7−1.979312814
ENSG000000793353.60E − 0.50.585897618ENSG000001425521.91E − 0.7−1.614114348
ENSG000001967354.68E − 0.53.57106113ENSG000002659822.45E − 0.7−1.351438572
ENSG000001021895.90E − 0.50.722100597ENSG000002604285.71E − 0.7−1.560721207
ENSG000000875020.0001420170.623605419ENSG000001821548.22E − 0.7−1.399962275
ENSG000001493080.0001634710.779073878ENSG000001603181.11E − 0.6−1.698375943
ENSG000001971470.0001773740.772560812ENSG000002652061.52E − 0.6−2.155095634
ENSG000001592560.0001830540.612216032ENSG000001754821.87E − 0.6−0.821303269
ENSG000001345450.0001888551.578550396ENSG000000898203.27E − 0.6−0.924629667

values < 0.05 were considered significant.