Factors Affecting ICU Stay and Length of Stay in the ICU in Patients with HELLP Syndrome in a Tertiary Referral Hospital
Table 2
Comparison of demographic data in patients staying and not staying in ICU.
Patients requiring ICU Group 1 n=32 (9.4%)
Patients not requiring ICU Group 2 n=310 (90.6%)
Age
27.3 (7.2)
30.4 (6.9)
0.792
Gravidity
3.3 (3.2)
3.9 (3.4)
0.129
Parity
2.1 (2.4)
2.4 (2.5)
0.378
Gestational age at delivery (week)
31.1 (4.0)
32.2 (4.0)
0.159
Hematocrit (%)
34.6 (6.0)
36.2 (5.6)
0.140
Hemoglobin (g/dl)
11.5 (2.0)
12.2 (2.3)
0.155
Platelet (K/uL)
73.6 (46.1)
106.3 (66.7)
0.001
ALT (U/L)
262.2 (225.6)
153.6 (166.5)
0.002
AST (U/L)
530.7 (384.9)
225.6 (252.4)
<0.001
LDH (IU/L)
1481.8 (642.8)
805.3 (489.4)
<0.001
Total bilirubin (mg/dl)
3.4 (2.8)
2.9 (2.3)
<0.001
Urea (mg/dl)
36.3 (27.1)
28.1 (13.9)
0.078
Creatinine (mg/dl)
1.3 (6.6)
1.2 (1.1)
0.001
Proteinuria (mg)
120 (68)
120 (60)
0.735
INR
1.8 (2.8)
1.1 (0.4)
0.074
Systolic blood pressure (mmHg)
156.4 (28.3)
155.4 (19.9)
0.561
Diastolic blood pressure (mmHg)
98.4 (18.9)
96.7 (11.9)
0.320
Blood transfusion
Yes
20 (62.5%)
73 (23.5%)
<0.001
No
12 (37.5%)
237 (76.5%)
Fresh frozen plasma (ml)
483.9 (814.9)
65.0 (215.2)
<0.001
Erythrocyte suspension (ml)
690.7 (924.6)
84.4 (260)
<0.001
Random suspension (ml)
583.3 (1100.7)
89.9 (356.0)
<0.001
Apheresis platelet suspension (ml)
612.5 (973.8)
84.9 (324.5)
<0.001
Dexamethasone treatment
Yes
26 (81.3%)
226 (72.9%)
0.144
No
6 (18.7%)
84 (27.1%)
Mississippi classification
Class 1
13 (40.6%)
38 (12.2%)
<0.001
Class 2
13 (40.6%)
151 (48.7%)
Class 3
6 (18.8%)
121 (39.1%)
Postpartum HELLP
Yes
10 (31.3%)
72 (23.2%)
0.317
No
22 (68.7%)
238 (76.8%)
Mode of delivery
Normal vaginal delivery
6 (18.75%)
50 (16.1%)
0.486
Cesarean section
26 (81.25%)
260 (83.9)
Multiple pregnancy
Yes
1 (3.1%)
9 (2.9%)
0.594
No
31 (96.9%)
301 (97.1%)
Place of birth
Delivery outside of the center
10 (31.3%)
55 (17.7%)
0.066
Delivery in the center
22 (68.7%)
255 (82.3%)
Maternal complication
ARF
6 (18.7%)
2 (0.6%)
0.074
GIB
1 (3.1%)
0
PRESS
6 (18.7%)
4 (1.3%)
DIC
4 (12.5%)
0
Sepsis
2 (6.25%)
0
Postpartum cardiomyopathy
2 (6.25%)
0
SAB
1 (3.1%)
0
Newborn mortality
Yes
1 (3.1%)
17 (5.5%)
0.568
No
31 (96.9%)
293 (94.5%)
Data are presented as mean ± SD or number (percent). Mann–Whitney U test, chi-square test, statistically significant (in bold). ICU: intensive care unit, ALT: alanine aminotransferase, AST: aspartate aminotransferase, LDH: lactate dehydrogenase, INR: international normalized ratio, ARF: acute renal failure, GIB: gastrointestinal bleeding, PRESS: posterior reversible encephalopathy syndrome, DIC: disseminated intravascular coagulation, AB: subarachnoid bleeding.
