Research Article
Influence of AGTR1 and ABCB1 Gene Polymorphism on the Curative Effect of Irbesartan
Table 2
The genotype frequency distribution in patient, control, and published article groups showed no significant difference.
| | n | Genotype frequency (%) | Allele frequency (%) | χ 2 | p |
| AGTR1 | rs5186 | | AA | AC | | A | C | | | Patient | 185 | 165 (89.2) | 20 (10.8) | | 94.6 | 5.4 | | | Control | 168 | 152 (90.5) | 16 (9.5) | | 95.2 | 4.8 | 0.622 | 0.733 |
| ABCB1 | rs1045642 | | CC | CT | TT | C | T | | | Patient | 185 | 58 (31.5) | 87 (48.0) | 40 (20.5) | 54.9 | 45.1 | | | Control | 168 | 54 (32.0) | 85 (50.3) | 30 (17.8) | 56.8 | 43.2 | 1.797 | 0.407 |
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