Research Article
Influence of AGTR1 and ABCB1 Gene Polymorphism on the Curative Effect of Irbesartan
Table 5
Effects of irbesartan in different genotype patients.
| Genotype | n | Highly effective | Effective | Ineffective | Total effective | Total effective ratio (%) | χ2 |
| ABCB1 | CC | 57 | 14 | 26 | 17 | 40 | 70.18 | χ 2 = 3.137, contingency coefficient = 0.129 p = 0.535 | CT | 89 | 19 | 38 | 32 | 57 | 64.04 | | TT | 39 | 10 | 21 | 8 | 31 | 79.49 | |
| AGTR1 | AA | 165 | 39 | 73 | 53 | 112 | 67.87 | χ 2 = 8.638, contingency coefficient = 0.211 p = 0.013 | AC | 20 | 4 | 12 | 4 | 16 | 80.00 |
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