Combination of Oxalobacter Formigenes and Veillonella Parvula in Gastrointestinal Microbiota Related to Bile-Acid Metabolism as a Biomarker for Hypertensive Nephropathy
Table 1
Characteristics information of experimental groups.
Characteristics
Normal n = 10
HBP n = 30
H-CKD n = 11
Normal vs HBP
HBP vs H-CKD
Demographics
Age, years median (Q1–Q3)
45 (42.0–51.5)
52.0 (40.0–65.3)
55.0 (43.5–64.5)
0.109
0.116
Gender, female, n(%)
5 (50.0%)
14 (46.7%)
5 (45.5%)
0.067
0.062
BMI, kg/m2, median, (Q1–Q3)
22.3 (21.0–24.3)
24.1 (22.9–25.8)
23.1 (22.4–24.8)
0.055
0.054
Behavior
Smoke, yes, n(%)
1 (10.0%)
12 (40.0%)
5 (45.6%)
0.05
0.055
Alcohol, yes, n(%)
2(20.0%)
10 (33.3%)
4 (36.4%)
0.074
0.084
Hypertension
History, yes, n(%)
3 (33.3%)
23 (76.7%)
8 (63.9%)
0.001
0.001
H grade-1, n(%)
—
4 (13.3%)
1 (9.0%)
—
—
H grade-2, n(%)
—
6 (20.0%)
6 (54.5%)
—
—
H grade-3, n(%)
—
6 (20.0%)
4 (39.1%)
—
—
Drug, no, n(%)
—
9 (30.0%)
6 (54.5%)
—
0.032
Time, n(%)
0–5 years
—
22 (73.3%)
7 (63.6%)
—
0.010
5–10 years
—
6 (20.0%)
3 (27.2%)
—
—
>10 years
—
2 (6.7%)
1 (9.1%)
—
—
BMI: body mass index; History: family history of early-onset cardiovascular and cerebrovascular disease; H grade: hypertensive grade; drug: Five categories of commonly used antihypertensive drugs; Time: time of hypertension or H-CKD.
