Blood Pressure Trajectories for 16 Years and the Development of Left Ventricular Hypertrophy and Increased Left Atrial Size: The Korean Genome and Epidemiology Study
Table 3
Association between mid-BP trajectories and increased left atrial volume index (>34.0 mL/m2).
Unadjusted
Model I
Model II
OR
95% CI
value
OR
95% CI
value
OR
95% CI
value
Total (n = 2,565)
1st group (lowest, n = 536)
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
2nd group (n = 928)
1.427
0.986–2.064
0.059
1.350
0.924–1.972
0.122
1.200
0.814–1.769
0.358
3rd group (n = 828)
2.064
1.438–2.961
<0.001
1.882
1.291–2.743
0.001
1.599
1.084–2.360
0.018
4th group (highest, n = 273)
2.385
1.539–3.698
<0.001
2.221
1.403–3.516
<0.001
1.944
1.212–3.118
0.006
Males (n = 1,267)
1st group (lowest, n = 137)
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
2nd group (n = 468)
1.190
0.613–2.310
0.607
1.133
0.581–2.207
0.715
0.897
0.452–1.778
0.755
3rd group (n = 480)
1.403
0.730–2.698
0.310
1.307
0.677–2.523
0.425
0.924
0.464–1.838
0.822
4th group (highest, n = 182)
1.658
0.801–3.432
0.173
1.498
0.720–3.120
0.280
1.061
0.494–2.279
0.879
Females (n = 1,298)
1st group (lowest, n = 399)
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
Ref.
2nd group (n = 460)
1.622
1.029–2.558
0.037
1.343
0.843–2.138
0.214
1.230
0.763–1.985
0.395
3rd group (n = 348)
2.992
1.918–4.667
<0.001
2.195
1.383–3.483
<0.001
2.005
1.249–3.218
0.004
4th group (highest, n = 91)
3.879
2.140–7.033
<0.001
2.818
1.524–5.209
0.001
2.732
1.455–5.128
0.002
CI: confidence interval, OR: odd ratio; Ref.: reference. Model I: adjusted for sex, and age. Model II: adjusted for sex, age, duration of obesity (years, Asian cut-off used, BMI ≥25 kg/m2), duration of diabetic mellitus (years, fasting glucose ≥126 mg/dL or medication), duration of hypercholesterolemia (years, total cholesterol ≥220 mg/dL), cigarette smoking (baseline 3 categories), alcohol drinking (baseline 3 categories), and exercise (baseline more than 30 min at least 2 times for a week, Y or N).
