Research Article
APOE Genetic Polymorphism rs7412 T/T Genotype May Be a Risk Factor for Essential Hypertension among Hakka People in Southern China
Table 1
Clinical characteristics of hypertensive patients and control participants.
| | Total (n = 4,884) | Hypertensive patients (n = 2,850) | Controls (n = 2,034) | values |
| Age, years | 66.69 ± 12.36 | 67.62 ± 11.76 | 65.39 ± 13.04 | <0.001 |
| Gender | Male, n(%) | 3160 (64.70) | 1761 (61.79) | 1399 (68.78) | <0.001 | Female, n(%) | 1724 (35.30) | 1089 (38.21) | 635 (31.22) | | History of smoking, n(%) | 1361 (27.87) | 694 (24.35) | 667 (32.79) | <0.001 | History of alcoholism, n(%) | 309 (6.33) | 132 (4.63) | 177 (8.70) | <0.001 | SBP, mmHg | 141.78 ± 27.02 | 150.96 ± 25.67 | 128.92 ± 23.38 | <0.001 | DBP, mmHg | 82.55 ± 15.64 | 86.27 ± 15.56 | 77.35 ± 14.22 | <0.001 | Hcy, μmol/L | 16.57 ± 7.97 | 16.95 ± 7.96 | 16.04 ± 7.97 | <0.001 | TG, mmol/L | 1.77 ± 1.73 | 1.82 ± 1.65 | 1.69 ± 1.82 | 0.008 | TC, mmol/L | 4.88 ± 1.41 | 4.95 ± 1.34 | 4.78 ± 1.50 | <0.001 | HDL-C, mmol/L | 1.27 ± 0.39 | 1.28 ± 0.38 | 1.25 ± 0.41 | 0.015 | LDL-C, mmol/L | 2.72 ± 0.98 | 2.77 ± 0.95 | 2.67 ± 1.03 | 0.001 | Apo-A1, g/L | 1.10 ± 0.33 | 1.13 ± 0.32 | 1.07 ± 0.34 | <0.001 | Apo-B, g/L | 0.85 ± 0.29 | 0.86 ± 0.28 | 0.82 ± 0.30 | <0.001 |
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