APOE Genetic Polymorphism rs7412 T/T Genotype May Be a Risk Factor for Essential Hypertension among Hakka People in Southern China

Table 1

Clinical characteristics of hypertensive patients and control participants.

	Total (n = 4,884)	Hypertensive patients (n = 2,850)	Controls (n = 2,034)	values
Age, years	66.69 ± 12.36	67.62 ± 11.76	65.39 ± 13.04	<0.001
Gender
Male, n(%)	3160 (64.70)	1761 (61.79)	1399 (68.78)	<0.001
Female, n(%)	1724 (35.30)	1089 (38.21)	635 (31.22)
History of smoking, n(%)	1361 (27.87)	694 (24.35)	667 (32.79)	<0.001
History of alcoholism, n(%)	309 (6.33)	132 (4.63)	177 (8.70)	<0.001
SBP, mmHg	141.78 ± 27.02	150.96 ± 25.67	128.92 ± 23.38	<0.001
DBP, mmHg	82.55 ± 15.64	86.27 ± 15.56	77.35 ± 14.22	<0.001
Hcy, μmol/L	16.57 ± 7.97	16.95 ± 7.96	16.04 ± 7.97	<0.001
TG, mmol/L	1.77 ± 1.73	1.82 ± 1.65	1.69 ± 1.82	0.008
TC, mmol/L	4.88 ± 1.41	4.95 ± 1.34	4.78 ± 1.50	<0.001
HDL-C, mmol/L	1.27 ± 0.39	1.28 ± 0.38	1.25 ± 0.41	0.015
LDL-C, mmol/L	2.72 ± 0.98	2.77 ± 0.95	2.67 ± 1.03	0.001
Apo-A1, g/L	1.10 ± 0.33	1.13 ± 0.32	1.07 ± 0.34	<0.001
Apo-B, g/L	0.85 ± 0.29	0.86 ± 0.28	0.82 ± 0.30	<0.001