The Association of Serum Anti-Lysosomal-Associated Membrane Protein-2 Antibody with Vasculitis Combined with Hypertension

Table 1

Demographic and laboratory features.

Variables	VAS-HTN (n = 51)	EH (n = 46)	HC (n = 46)	value	AAV (n = 20)	PAN (n = 24)	TA (n = 7)
Demographic features
Age (years)	40.22 ± 9.62	43.74 ± 9.22	42.61 ± 15.87	0.287	42.50 ± 8.78	38.54 ± 9.45	38.00 ± 12.29
Females, n (%)	22 (43.1)	15 (32.6)	26 (56.5)	0.121	11 (55.0)	7 (29.2)	4 (57.1)
SBP (mmHg)	164.65 ± 27.33	142.50 ± 17.59	118.26 ± 11.34	<0.001	161.95 ± 29.09	167.08 ± 26.16	164.00 ± 29.54
DBP (mmHg)	104.20 ± 19.26	88.11 ± 11.31	73.13 ± 8.55	<0.001	99.05 ± 24.10	110.00 ± 14.59	99.00 ± 13.40
BMI (kg/m^2)	25.76 ± 3.99	27.05 ± 4.25	23.32 ± 3.03	<0.001	25.46 ± 3.48	26.39 ± 4.58	24.44 ± 3.14
Laboratory features
ESR (mm/h)	18.43 ± 14.21	10.22 ± 7.77	9.23 ± 5.15	0.003	20.80 ± 15.43	15.25 ± 15.95	22.57 ± 14.41
Scr (umol/L)	106.62 ± 45.43	66.33 ± 16.56	72.36 ± 12.44	<0.001	107.33 ± 55.64	108.79 ± 38.51	97.14 ± 43.30
WBC (×10^9/L)	7.37 ± 2.83	6.22 ± 1.43	6.53 ± 1.83	0.026	6.70 ± 2.79	7.33 ± 1.80	9.42 ± 4.85
HB (g/L)	138.59 ± 20.95	145.17 ± 11.99	150.38 ± 15.18	0.015	134.35 ± 25.09	145.58 ± 15.96	126.71 ± 16.31
PLT (×109/L)	245.10 ± 106.73	254.65 ± 67.74	262.50 ± 44.85	0.552	252.40 ± 95.19	222.63 ± 80.71	301.29 ± 188.09
ANCA (+), n (%)	8 (15.7)	0 (0)	0 (0)	<0.001	7 (35.0)	0 (0)	1 (14.3)
Hs-CRP (mg/L)	2.82 (0.91 to 8.35)	1.04 (0.42 to 2.64)	—	0.001	2.64 (0.77 to 7.72)	2.97 (1.04 to 8.17)	5.59 (0.72 to 26.99)
Proteinuria (+), n (%)	20 (39.2)	0 (0)	0 (0)	<0.001	7 (35.0)	11 (45.8)	2 (28.6)
Hematuria (+), n (%)	7 (13.7)	0 (0)	0 (0)	<0.001	3 (15.0)	3 (12.5)	1 (14.3)
24-hour proteinuria (g)	0.20 (0.06 to 0.61)	0.06 (0.04 to 0.09)	—	<0.001	0.12 (0.05 to 0.37)	0.28 (0.12 to 0.71)	0.23 (0.03 to 0.79)
Anti-LAMP-2 (ng/ml)	127.98 ± 54.98	53.59 ± 35.51	55.21 ± 25.09	<0.001	107.90 ± 41.13	154.34 ± 54.65	94.98 ± 54.65

Continuous variables are shown as median and interquartile range or as mean ± standard deviation.