Review Article

Summary of Known Genetic and Epigenetic Modification Contributed to Hypertension

Table 2

A summary of genetic variant associated with polygenic hypertension.

GenesPolymorphism(s)/markers

AGT geneM235T and T174M variant
ACE geneInsertion/deletion (I/D) polymorphism within exon 16, DD genotype, D allele
GNB3 geneC825T allele
IL-6 gene−572C/G promoter polymorphism
TNF-α−308G/A polymorphism
TNF-αG308A polymorphism