Da-Chuan-Xiong Decoction Ameliorates Sodium Sensitivity and Plasma Norepinephrine via Attenuation of Brain Oxidative Stress in the DOCA-Salt Hypertensive Rats

Table 1

Effects of DCXD on heart index, kidney index, creatinine clearance, and urine protein in DOCA-salt hypertensive rats.

Parameter	Sham group	DOCA-salt group	DCXD-5 group	DCXD-2.5 group	AML group
HW/BW (mg/g)	3.11 ± 0.13	3.86 ± 0.11	3.42 ± 0.05^#	3.63 ± 0.11	3.47 ± 0.06
KW/BW (mg/g)	5.1 ± 0.10	6.48 ± 0.18	5.53 ± 0.22^##	5.66 ± 0.16^#	5.73 ± 0.22^#
Creatinine clearance (ml/min)	2.22 ± 0.26	0.47 ± 0.13	2.02 ± 0.31^##	1.34 ± 0.33	1.07 ± 0.26^#
Urine protein (mg/day)	4.21 ± 1.15	15.73 ± 3.44	7.62 ± 0.62^#	10.31 ± 0.57	8.46 ± 0.41^#

HW/BW, heart weight/body weight ratio; KW/BW, kidney weight/body weight ratio; AML, amlodipine. Data are presented as mean ± SEM (n = 6). vs. the sham group; ^# and ^## vs. the DOCA-salt group.