Activation of T Lymphocytes in Response to Persistent Bacterial Infection: Induction of CD11b and of Toll-Like Receptors on T Cells
Figure 5
Expression of TLR on peripheral CD8+ cells in patients with implant-associated osteomyelitis and in healthy donors: (a) by cytofluorometry, expressions of TLR1, TLR2, and TLR4 on CD8+ cells was determined. Each dot represents a patient or a donor, respectively. The horizontal bars represent the median values. The mean values for TLR2 and TLR4 were different between patients and donors as calculated by ANOVA. (b) CD8+CD28+CD11b+ expressing TLR1, TLR2, or TLR4 were quantified by cytofluorometry at the day of surgery (before) or 6 to 8 days later (after) when the infection was resolved. Each symbol refers to an individual patient; the line connects the values before and after surgery.
