Activation of T Lymphocytes in Response to Persistent Bacterial Infection: Induction of CD11b and of Toll-Like Receptors on T Cells
Figure 7
Synthesis of interferon by the infiltrated T cells. (a) The infiltrated T cells were recovered and cultured for 16 hours in the presence of brefeldin 1. The cells were permeabilised, and interferon was determined by cytofluorometry, as was CD4 and CD8. The gate was set for CD4+ or CD8+, respectively. Up to 90% of cells contained interferon (b) Data of 7 patients are summarised. Shown are values obtained for the infiltrated T cells (local), for T cells of the peripheral blood of patients, and for healthy donors as well (differences of the mean values were calculated by ANOVA and found to be different with a ).
