The Role of Bacteria and Pattern Recognition Receptors in GvHD
Figure 1
Treatment-related mortality and SNPs of innate immunity. SNPs 8,12 and 13 of NOD2 () and the T300A. SNP of ATG16L1 () were assessed by PCR in patients receiving allogeneic SCT and their respective HLA-identical sibling donors. Cumulative treatment related mortality as calculated by Kaplan-Meier method is shown in relation to absence of any SNPs (wt, wild-type) or presence of SNPs (variant, var) in recipients (R) and/or donors (D). Both associations were significant by log rank tests ( for NOD2, for ATG16L1).
