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Figure 4: Schematic diagram of cardiac infarct size (blue region) after acute ischemia and reperfusion (I/R) and neutrophil CXCR2 downregulation by deletion of myeloid differentiation factor 88 (MyD88) globally (right top) and targeted to leukocytes only (right bottom). (Schmid-Schönbein, [103], used with permission).