International Journal of Inflammation / 2011 / Article / Tab 2

Research Article

Gene Profiling of Aortic Valve Interstitial Cells under Elevated Pressure Conditions: Modulation of Inflammatory Gene Networks

Table 2

Upregulated genes related to inflammation. All genes had a .

Ensembl Gene IDGene nameDescriptionFold change

ENSSSCG00000014986MMP3 Matrix metallopeptidase 3 (stromelysin 1, progelatinase)159.845
ENSSSCG00000015385IL6Interleukin 6 (interferon, beta 2)117.817
ENSSSCG00000006286SELESelectin E74.336
ENSSSCG00000011727PTX3Pentraxin 3, long41.052
ENSSSCG00000008087IL1BInterleukin 1, beta20.185
ENSSSCG00000017482CSF3Granulocyte colony-stimulating factor Precursor (G-CSF)15.267
ENSSSCG00000006588S100A9S100 calcium binding protein A99.664
ENSSSCG00000008959CXCL2CXCL29.498
ENSSSCG00000008090IL1AInterleukin 1, alpha9.361
ENSSSCG00000017705CCL5Chemokine (C-C motif) ligand 59.339
ENSSSCG00000017721CCL8Chemokine (C-C motif) ligand 88.386
ENSSSCG00000006288SELPSelectin P (granule membrane protein 140 kDa, antigen CD62)8.002
ENSSSCG00000014985MMP1Matrix metallopeptidase 1 (interstitial collagenase)7.976
ENSSSCG00000008953IL8Interleukin 87.279
ENSSSCG00000008957CXCL5Alveolar macrophage chemotactic factor 2 Precursor (Alveolar macrophage chemotactic factor II) (AMCF-II)7.189
ENSSSCG00000008975CXCL9Chemokine (C-X-C motif) ligand 96.687
ENSSSCG00000017723CCL2Chemokine (C-C motif) ligand 25.243
ENSSSCG00000012853IRF7Interferon regulatory factor 74.625
ENSSSCG00000013655ICAM1Intercellular adhesion molecule 14.041
ENSSSCG00000001050EDN1Endothelin 13.383
ENSSSCG00000004789THBS1Thrombospondin 13.113
ENSSSCG00000001404TNFTumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor Ligand superfamily member 2)(TNF-a)(Cachectin)2.626
ENSSSCG00000010414CXCL12Chemokine (C-X-C motif) ligand 122.62
ENSSSCG00000000708TNFRSF1ATumor necrosis factor receptor superfamily, member 1A2.327
ENSSSCG00000009002TLR2Toll-like receptor 22.157
ENSSSCG00000003065PLAURPlasminogen activator, urokinase receptor1.937
ENSSSCG00000009477EDNRB Endothelin B receptor Precursor (ET-B)(Endothelin receptor nonselective type)1.859
ENSSSCG00000011942CD47CD47 molecule1.858
ENSSSCG00000001346ABCF1ATP-binding cassette subfamily F member 11.786
ENSSSCG00000010312PLAUPlasminogen activator, urokinase1.747
ENSSSCG00000013181SERPING1Serpin peptidase inhibitor, clade G (C1 inhibitor), member 11.71
ENSSSCG00000007440CD40CD40 molecule, TNF receptor superfamily member 51.674
ENSSSCG00000004156IFNGR1Interferon gamma receptor 11.6
ENSSSCG00000001849ANPEPAlanyl (membrane) aminopeptidase1.547
ENSSSCG00000011322CCR1Chemokine (C-C motif) receptor 11.542
ENSSSCG00000000244PPBPPlatelet basic protein Precursor (PBP)(C-X-C motif chemokine 7)(Small-inducible cytokine B7)1.533
ENSSSCG00000013551C3Complement component 31.514

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