Ghrelin Protects against the Detrimental Consequences of Porphyromonas gingivalis-Induced Akt Inactivation through S-Nitrosylation on Salivary Mucin Synthesis
Figure 3
Effect of ghrelin on P. gingivalis LPS-induced changes in mucin synthesis and the expression of cNOS activity in the salivary gland acinar cells. The cells, preincubated with the indicated concentrations of ghrelin, were treated with the LPS at 100 ng/mL and incubated for 16 h in the presence of [3H]glucosamine as a marker of mucin synthesis. Values represent the means ± SD of five experiments. * compared with that of control. ** compared with that of LPS alone.
