Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans

Figure 2

Distribution of CXCL10 measurements from each patient across quartiles. Atherosclerotic plaques were obtained from 106 patients during carotid endarterectomy. In the plaque segment directly adjacent to the culprit lesion, the content of the chemokine CXCL10 was measured by ELISA. Based on these measurements, patients were divided into one of four quartiles according to the CXCL10 concentration. Quartile 1 represents the lesions with the lowest CXCL10 values, whereas quartile 4 contains the highest. This figure shows the individual measurements for all patients and the distribution across each quartile of plaque CXCL10. Horizontal bars represent the median concentration of each quartile.