Significantly decreased quantity of aerobic bacteria in IBS than healthy control and increased concentration of Lactobacillus species in D-IBS patients than healthy control
Decreased quantity of Clostridium thermosuccinogens in IBS-D patients and increased quantity of Ruminococcus torque in IBS-D patients than healthy control. Ruminococcus bromii was more abundant in IBS-C than healthy control
% G + C profiling and fractioned DNA sequencing followed by q PCR
Significantly increased quantity of Proteobacteria and Firmicutes and reduced quantity of Actinobacteria and Bacteroidetes in IBS-D patients than healthy control
Significant difference in gut microbiota in IBS patients and healthy control along with more variation in the gut microbiota in control than IBS subjects
Significantly increased number of Bacteroidetes and Synergistetes and reduced number of Actinobacteria, Bacilli, Flavobacteria, and Epsilonproteobacteria in IBS than control
IBS: irritable bowel syndrome; IBS-D: diarrhea predominant IBS; IBS-C: constipation predominant IBS; PCR: polymerase chain reaction; DGGE: denaturation gradient gel electrophoresis; q PCR: real time PCR; FISH: fluorescent in situ hybridization; TRAC: transcript analysis with the aid of affinity capture.