Protective Effect of Melatonin on Acute Pancreatitis
Figure 2
Effect of intraperitoneal (i.p.) application of melatonin or its precursor, L-tryptophan, on concentrations of antioxidative enzyme superoxide dismutase (SOD) and lipid peroxidation products (MDA + 4-HNE) in the pancreatic tissue taken from rats with acute pancreatitis (AP). Melatonin or its precursor, L-tryptophan, was applied as explained on Figure 1. Control—intact rats. Means ± SEM from the separate experiments, each performed on 8–10 rats. Asterisk indicates significant increase above the value detected in AP rats alone. Cross indicates significant decreases below the value detected in AP rats alone.
