Pharmacological Evaluation of the SCID T Cell Transfer Model of Colitis: As a Model of Crohn's Disease
Figure 2
Histological changes in colon after adoptive transfer. Representative photomicrographs of histological changes leading to a progressively higher score from (a) to (f): (a) normal, (b) mild inflammation restricted to the mucosa, (c) moderate mucosal inflammation, (d) severe inflammation extending to submucosa, moderate to severe crypt degeneration, (e) severe transmural inflammation, moderate to severe crypt degeneration, (f) as (e) but with ulceration. Original magnification ×25 for (a-b) and ×10 for (c–f).
